Histologic Basis of MRI in prostate peripheral zone: determination of the relationships between sub-cellular components and ADC, T2, Ktrans and ve
نویسندگان
چکیده
D. L. Langer, T. H. van der Kwast, A. J. Evans, J. Trachtenberg, B. C. Wilson, and M. A. Haider Joint Department of Medical Imaging, Princess Margaret Hospital, University Health Network and Mount Sinai Hospital, Toronto, Ontario, Canada, Institute of Medical Sciences, University of Toronto, Toronto, Ontario, Canada, Department of Pathology and Laboratory Medicine, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada, Department of Surgical Oncology, Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada, Medical Biophysics, University of Toronto, Ontario Cancer Institute, Toronto, Ontario, Canada
منابع مشابه
Evaluation of the accuracy of dynamic contrast enhanced MRI in the diagnosis of invasive prostate neoplasm using pathological findings
Background: Prostate cancer is the most common malignancy in men and the second leading cause of death in all countries of the world. The exact mechanism of prostate cancer is not known. On the other hand, early detection of prostate cancer can lead to a complete cure. Several clinical experiments including Digital Rectum Examination (DRE), biochemistry such as Prostate Specific Antigen (PSA), ...
متن کاملThe Correlations Between MRI Perfusion, Diffusion Parameters, and 18F-FDG PET Metabolic Parameters in Primary Head-and-Neck Cancer
This study aimed to investigate the relationships among parameters from dynamic contrast-enhanced (DCE) MRI, diffusion-weighted MRI (DWI), and F-fluorodeoxyglucose (F-FDG) PET in patients with primary head-and-neck squamous cell carcinoma (HNSCC).A total of 34 patients with primary HNSCC underwent DCE-MRI, DWI, and F-FDG PET before treatment. The perfusion parameters (Ktrans, Ktransmax, Kep, Ve...
متن کاملAssociations between 18F-FDG-PET, DWI, and DCE Parameters in Patients with Head and Neck Squamous Cell Carcinoma Depend on Tumor Grading
Our purpose was to analyze associations between positron emission tomography (PET), diffusion weighted imaging (DWI), and dynamic contrast-enhanced (DCE) imaging in patients with head and neck squamous cell carcinoma (HNSCC). The study involved 34 patients (9 women, 25 men, mean age: 56.7 ± 10.2 years). In all patients a simultaneous 18F-FDG-PET/MR was performed. DWI was obtained by using of an...
متن کاملThe Impact of Arterial Input Function Determination Variations on Prostate Dynamic Contrast-Enhanced Magnetic Resonance Imaging Pharmacokinetic Modeling: A Multicenter Data Analysis Challenge.
Dynamic contrast-enhanced MRI (DCE-MRI) has been widely used in tumor detection and therapy response evaluation. Pharmacokinetic analysis of DCE-MRI time-course data allows estimation of quantitative imaging biomarkers such as Ktrans(rate constant for plasma/interstitium contrast reagent (CR) transfer) and ve (extravascular and extracellular volume fraction). However, the use of quantitative DC...
متن کاملProstate cancer radiomics: A study on IMRT response prediction based on MR image features and machine learning approaches
Introduction: To develop different radiomic models based on radiomic features and machine learning methods to predict early intensity modulated radiation therapy (IMRT) response. Materials and Methods: Thirty prostate patients were included. All patients underwent pre ad post-IMRT T2 weighted and apparent diffusing coefficient (ADC) magnetic resonance imagi...
متن کامل